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KETamine sedation as neuroprotective agent following out-of-hospital cardiac arrest (OHCA) - the KETOHCA trial.

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-515987-29-00
Enrollment
282
Registered
2024-10-01
Start date
2024-12-11
Completion date
Unknown
Last updated
2025-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Out-of-hospital cardiac arrest

Brief summary

Neuron-specific enolase (NSE) measured 48 hours after OHCA

Detailed description

1. Death from all causes at 180 days after cardiac arrest. 2. CPC- and mRS score at hospital discharge and 180-240 days after cardiac arrest.

Interventions

DRUGS-ketamin "Pfizer" injektionsvæske
DRUGopløsning

Sponsors

Rigshospitalet
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Neuron-specific enolase (NSE) measured 48 hours after OHCA

Secondary

MeasureTime frame
1. Death from all causes at 180 days after cardiac arrest. 2. CPC- and mRS score at hospital discharge and 180-240 days after cardiac arrest.

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026