Patients have peristent peripheral neuropathic pain. They are not rare diseases.
Conditions
Brief summary
Pregabalin response to pain. Pain intensity and interference assessed by numeric rating scale
Detailed description
Pregabalin effect on sleep stages. 1-night Ambulatory Polysomnography (NREM stage III)., Sleep disturbance associations to brain network connectivity. Brain fMRI for brain network connectivity, Sleep disturbance associations to choroid plexus volume in brain fMRI. Brain fMRI for choroid plexus volume measures, Pregabalin effect on circadian rhythms. 1-week actigraphy and OURA-ring, Pregabalin effect on body temperature during sleep. 1-night body temperature measurement by iButton
Interventions
DRUGPregabalin Pfizer 150 mg hard capsules
DRUGLyrica 25 mg hard capsules
DRUGLyrica 75 mg hard capsules
Sponsors
HUS-Yhtymae
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregabalin response to pain. Pain intensity and interference assessed by numeric rating scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Pregabalin effect on sleep stages. 1-night Ambulatory Polysomnography (NREM stage III)., Sleep disturbance associations to brain network connectivity. Brain fMRI for brain network connectivity, Sleep disturbance associations to choroid plexus volume in brain fMRI. Brain fMRI for choroid plexus volume measures, Pregabalin effect on circadian rhythms. 1-week actigraphy and OURA-ring, Pregabalin effect on body temperature during sleep. 1-night body temperature measurement by iButton | — |
Countries
Finland
Outcome results
None listed