Skip to content

Benefits of early discontinuation of antibiotic therapy versus standard management in elderly patients hospitalized for viral infection: a multicenter, open-label, cluster-randomized controlled study

Status
Not yet recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-515695-13-00
Acronym
PI2023_843_0153
Enrollment
256
Registered
2025-02-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elderly patients hospitalized for viral infections

Brief summary

Number of days without antibiotics at D30

Detailed description

Side effects of antibiotics: (collected in the eCRF at each occurrence) o Clostridial colitis, o venitis, o diarrhea, o nausea, o vomiting, o BMR germ colonization, o allergy, o other attributable effect: specify, Other complications: o nosocomial infections, o complications of decubitus, o intra-hospital mortality from any cause, o confusion, o other complication attributable to hospitalization and the reason for hospitalization: specify, Mortality at M1 and M3 or autonomy: ADL and IADL score at M1 and M3 (compared to those 15 days before hospitalization), Duration of hospitalization in acute care (in days), Number of days without antibiotics at M3

Interventions

DRUGPYOSTACINE 500 mg
DRUGcomprimé pelliculé
DRUGCEFTRIAXONE

Sponsors

Centre Hospitalier Universitaire Amiens Picardie
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Number of days without antibiotics at D30

Secondary

MeasureTime frame
Side effects of antibiotics: (collected in the eCRF at each occurrence) o Clostridial colitis, o venitis, o diarrhea, o nausea, o vomiting, o BMR germ colonization, o allergy, o other attributable effect: specify, Other complications: o nosocomial infections, o complications of decubitus, o intra-hospital mortality from any cause, o confusion, o other complication attributable to hospitalization and the reason for hospitalization: specify, Mortality at M1 and M3 or autonomy: ADL and IADL score at M1 and M3 (compared to those 15 days before hospitalization), Duration of hospitalization in acute care (in days), Number of days without antibiotics at M3

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026