DERMOS study : Influence of dermocorticoids on bone mineral density in patients with bullous pemphigoid.

Conditions

Bullous pemphigoid

Brief summary

Variation in bone mineral density (BMD) expressed in g/cm² at level of the lumbar spine between the initial BMD at M0 and that achieved at the end of theoretical treatment at M6.

Detailed description

Correlation between total exposure to topical corticosteroids and reduction in BMO, Variation in BMO between M0 and M3 at the lumbar spine., Variation in BMO between M0 and M3 and M6 at the hip., Varation in plasma concentrations of corrected serum calcium, phosphorus, 25 OH vitamin D and cortisolemia at 8 a.m. between M0, M3 and M6., Frequency of fractures (axial and/or peripheral) according to exposure to corticosteroids at M6., Correlation between these different biological parameters and density bone mineral at M0, M3 and M6.

Related papers

No related papers found yet.

Papers published before 2007-09-01 may not appear yet. Historical indexing is in progress.

Interventions

DRUGCLOBETASOL PROPIONATE

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Variation in bone mineral density (BMD) expressed in g/cm² at level of the lumbar spine between the initial BMD at M0 and that achieved at the end of theoretical treatment at M6.	—

Secondary

Measure	Time frame
Correlation between total exposure to topical corticosteroids and reduction in BMO, Variation in BMO between M0 and M3 at the lumbar spine., Variation in BMO between M0 and M3 and M6 at the hip., Varation in plasma concentrations of corrected serum calcium, phosphorus, 25 OH vitamin D and cortisolemia at 8 a.m. between M0, M3 and M6., Frequency of fractures (axial and/or peripheral) according to exposure to corticosteroids at M6., Correlation between these different biological parameters and density bone mineral at M0, M3 and M6.	—

Measure

Time frame

Correlation between total exposure to topical corticosteroids and reduction in BMO, Variation in BMO between M0 and M3 at the lumbar spine., Variation in BMO between M0 and M3 and M6 at the hip., Varation in plasma concentrations of corrected serum calcium, phosphorus, 25 OH vitamin D and cortisolemia at 8 a.m. between M0, M3 and M6., Frequency of fractures (axial and/or peripheral) according to exposure to corticosteroids at M6., Correlation between these different biological parameters and density bone mineral at M0, M3 and M6.

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Countries

France

Outcome results

None listed