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Measuring of the duration of action of different doses of rocuronium-induced neuromuscular block in infants during surgical treatment of craniosynostosis - a prospective, case-controlled study

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-515545-41-00
Acronym
AITT 2023/8
Enrollment
20
Registered
2024-09-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

a prospective, case-controlled study

Brief summary

The primary endpoint of both the first and second phase of the study is to investigate the extent to which sevoflurane used to maintain inhalational anaesthesia and propofol used to maintain total intravenous anaesthesia potentiate the pharmacokinetic properties of rocuronium at different doses. The translational clinical utility of this may be that knowledge in this age population will contribute to the safe implementation of reversal of muscle relaxant action.

Interventions

DRUGRocuronium bromide hameln 10 mg/ml oldatos injekció/infúzió

Sponsors

University Of Debrecen
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
0 Years to 17 Years

Design outcomes

Primary

MeasureTime frame
The primary endpoint of both the first and second phase of the study is to investigate the extent to which sevoflurane used to maintain inhalational anaesthesia and propofol used to maintain total intravenous anaesthesia potentiate the pharmacokinetic properties of rocuronium at different doses. The translational clinical utility of this may be that knowledge in this age population will contribute to the safe implementation of reversal of muscle relaxant action.

Countries

Hungary

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026