Lynch syndrome, which is increasing the risk of developing colorectal cancer
Conditions
Brief summary
Occurrence of any colorectal neoplasia (both benign and malignant tumors)
Detailed description
The number of colorectal neoplasia (both benign and malignant tumors) per patient, The tumor progress in the 4 ordered stages, The dependence of treatment effects on history of colorectal cancer, sex and patients age (<45 years and ≥45 years), Safety data are described and compared between groups in an exploratory manner
Interventions
DRUGPentasa Sachet 2 g depotgranulat
DRUGPentasa PLACEBO Sachet 2g in the granule formulation specifically designed to resemble the active drug product
Sponsors
Karolinska Institutet
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of any colorectal neoplasia (both benign and malignant tumors) | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of colorectal neoplasia (both benign and malignant tumors) per patient, The tumor progress in the 4 ordered stages, The dependence of treatment effects on history of colorectal cancer, sex and patients age (<45 years and ≥45 years), Safety data are described and compared between groups in an exploratory manner | — |
Countries
Denmark, Sweden
Outcome results
None listed