FIGO stage III high grade serous ovarian cancer, peritoneal cancer, or fallopian tube carcinoma
Conditions
Brief summary
intratumoral Pt concentration at the end of perfusion after 90 min (in ng/mg wet tissue)
Detailed description
Toxicity evaluation (CTCAE 5.0), Pt concentration in normal tissue (in ng/mg wet tissue), Pt concentration in tumor tissue after 30 min and 60 min of perfusion (in ng/mg wet tissue), Concentration versus time curve and AUC of intra-peritoneal Pt during perfusion, Cmax, tmax, terminal t ½ in perfusate, clearance from perfusate at the end of perfusion, Recurrence-free survival (RFS) and Overall survival (OS)
Interventions
Sponsors
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intratumoral Pt concentration at the end of perfusion after 90 min (in ng/mg wet tissue) | — |
Secondary
| Measure | Time frame |
|---|---|
| Toxicity evaluation (CTCAE 5.0), Pt concentration in normal tissue (in ng/mg wet tissue), Pt concentration in tumor tissue after 30 min and 60 min of perfusion (in ng/mg wet tissue), Concentration versus time curve and AUC of intra-peritoneal Pt during perfusion, Cmax, tmax, terminal t ½ in perfusate, clearance from perfusate at the end of perfusion, Recurrence-free survival (RFS) and Overall survival (OS) | — |
Countries
Netherlands
Outcome results
None listed