Intravenous dexmedetomidine as an adjuvant to locoregional anesthesia in pediatric surgery: a prospective, randomized, double-blind, placebo-controlled study. DEXPED

Conditions

Loco-regional anesthesia in pediatric surgery

Brief summary

Number of patients using a rescue analgesic (Nalbuphine, Nubain®) in the PACU between the two arms

Detailed description

Assessment of postoperative pain using the Face Legs Activity Cry Consolability (FLACC) scale: on admission and every 15 minutes until discharge from the PACU, then before returning home, Intraoperative morphine consumption: Sufentanil, number of re-injections (0.1 µg/kg) required, Dose in milligrams of emergency analgesics in the PACU, Incidence of opioid-related side effects (respiratory complications, postoperative nausea and vomiting), Length of stay (from PACU entry to discharge based on Aldrete score > 9), Incidence of emergence delirium in the PACU according to the Pediatric Anesthesia Emergence Delirium (PAED) scale, Post-Hospitalization Behavior Questionnaire at 7 days, 3, and 6 months, Postoperative Pain Measure For Parents at 7 days, 3, and 6 months, Post-operative quality of life questionnaire pedsQL at 7 days, 3 and 6 months

Related papers

No related papers found yet.

Interventions

DRUGDEXMEDETOMIDINE

DRUGSODIUM CHLORIDE

Eligibility

Sex/Gender

All

Age

0 Years to 17 Years

Design outcomes

Primary

Measure	Time frame
Number of patients using a rescue analgesic (Nalbuphine, Nubain®) in the PACU between the two arms	—

Secondary

Measure	Time frame
Assessment of postoperative pain using the Face Legs Activity Cry Consolability (FLACC) scale: on admission and every 15 minutes until discharge from the PACU, then before returning home, Intraoperative morphine consumption: Sufentanil, number of re-injections (0.1 µg/kg) required, Dose in milligrams of emergency analgesics in the PACU, Incidence of opioid-related side effects (respiratory complications, postoperative nausea and vomiting), Length of stay (from PACU entry to discharge based on Aldrete score > 9), Incidence of emergence delirium in the PACU according to the Pediatric Anesthesia Emergence Delirium (PAED) scale, Post-Hospitalization Behavior Questionnaire at 7 days, 3, and 6 months, Postoperative Pain Measure For Parents at 7 days, 3, and 6 months, Post-operative quality of life questionnaire pedsQL at 7 days, 3 and 6 months	—

Measure

Time frame

Assessment of postoperative pain using the Face Legs Activity Cry Consolability (FLACC) scale: on admission and every 15 minutes until discharge from the PACU, then before returning home, Intraoperative morphine consumption: Sufentanil, number of re-injections (0.1 µg/kg) required, Dose in milligrams of emergency analgesics in the PACU, Incidence of opioid-related side effects (respiratory complications, postoperative nausea and vomiting), Length of stay (from PACU entry to discharge based on Aldrete score > 9), Incidence of emergence delirium in the PACU according to the Pediatric Anesthesia Emergence Delirium (PAED) scale, Post-Hospitalization Behavior Questionnaire at 7 days, 3, and 6 months, Postoperative Pain Measure For Parents at 7 days, 3, and 6 months, Post-operative quality of life questionnaire pedsQL at 7 days, 3 and 6 months

—

Countries

France

Outcome results

None listed