Knee osteoarthritis
Conditions
Brief summary
Absolute change from baseline to Week 54 of the pain subscale score of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) (5 items), Absolute change from baseline to Week 54 of the WOMAC physical function subscale score (17 items)
Detailed description
Absolute change from baseline to Week 54 of Synovitis based on 11-point synovitis score, Absolute change from baseline in cartilage thickness (ThC) in the medial femorotibial compartment (MFTC), assessed by MRI at 2 years (Week 104) using quantitative image analysis method
Interventions
Sponsors
Peptinov
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute change from baseline to Week 54 of the pain subscale score of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) (5 items), Absolute change from baseline to Week 54 of the WOMAC physical function subscale score (17 items) | — |
Secondary
| Measure | Time frame |
|---|---|
| Absolute change from baseline to Week 54 of Synovitis based on 11-point synovitis score, Absolute change from baseline in cartilage thickness (ThC) in the medial femorotibial compartment (MFTC), assessed by MRI at 2 years (Week 104) using quantitative image analysis method | — |
Countries
Czechia, Denmark, France, Poland, Romania
Outcome results
None listed