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Exploration of the pathophysiology of cluster headache (AVF) in PET-MRI using [18F]F13640 F13640-AVF

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-513873-36-00
Enrollment
12
Registered
2024-09-12
Start date
2022-02-28
Completion date
Unknown
Last updated
2025-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases

Brief summary

Comparison of the different density maps of the functional receptors in the 2 periods Comparison of different regional cerebral blood flow maps in the 2 periods Correlations of BOLD fluctuations between distant regions: functional connectivity of patients in the 2 periods

Detailed description

Comparison of the different density maps of functional 5-HT1A receptors during the 2 periods before the crisis, during the crisis and post-attack. Comparison of different regional cerebral blood flow maps during the 2 periods before the attack, during the attack and post-attack. Correlations of BOLD fluctuations between distant regions: functional connectivity of patients during the 2 periods before the attack, during the attack and post-attack. Variation of the BOLD signal in active period duri

Interventions

None listed

Sponsors

Hospices Civils De Lyon
Lead SponsorOTHER

Eligibility

Sex/Gender
Male
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
Comparison of the different density maps of the functional receptors in the 2 periods Comparison of different regional cerebral blood flow maps in the 2 periods Correlations of BOLD fluctuations between distant regions: functional connectivity of patients in the 2 periods

Secondary

MeasureTime frame
Comparison of the different density maps of functional 5-HT1A receptors during the 2 periods before the crisis, during the crisis and post-attack. Comparison of different regional cerebral blood flow maps during the 2 periods before the attack, during the attack and post-attack. Correlations of BOLD fluctuations between distant regions: functional connectivity of patients during the 2 periods before the attack, during the attack and post-attack. Variation of the BOLD signal in active period duri

Countries

France

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026