Patients with high-grade serous epithelial ovarian, tubal or primary peritoneal cancers
Conditions
Brief summary
Identification of clinical/biological/pharmacokinetic/therapeutic factors leading to hematological and/or renal toxicology(s).
Detailed description
Relation of the average pharmacokinetic parameters observed in patients according to the clinical/biological/therapeutic and dietary parameters studied., Relationship between the pharmacokinetic parameters measured and the PFS at 24 months., Creation of predictive models using logistic models or PK-PD models with direct or indirect effects., Measurement of quality of life and correlation with observed toxicities.
Interventions
Sponsors
Hospices Civils De Lyon
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identification of clinical/biological/pharmacokinetic/therapeutic factors leading to hematological and/or renal toxicology(s). | — |
Secondary
| Measure | Time frame |
|---|---|
| Relation of the average pharmacokinetic parameters observed in patients according to the clinical/biological/therapeutic and dietary parameters studied., Relationship between the pharmacokinetic parameters measured and the PFS at 24 months., Creation of predictive models using logistic models or PK-PD models with direct or indirect effects., Measurement of quality of life and correlation with observed toxicities. | — |
Countries
France
Outcome results
None listed