Immune thRombocytopenia
Conditions
Brief summary
Platelet production of thromboxane B2 (TXB2) 24 hours after a 75 mg aspirin intake
Detailed description
Platelet function by light transmission agregometry (LTA) 24 four hours after a 75 mg aspirin intake;, platelet production of TXB2 by lipidomic and platelet function by LTA at H2 and H12 after a75 mg aspirin intake, arterial thromboses identified in the CARMEN registry., Measurement of platelet TXB2 synthesis after platelet stimulation by arachidonic acid at H2 and H12 from a dose of 75 mg of AAS. 12-HETE produced by lymphoxygenase and quantified in the same mass spectrometry profile as TXB2 will also be taken into account.
Interventions
Sponsors
Centre Hospitalier Universitaire De Toulouse
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet production of thromboxane B2 (TXB2) 24 hours after a 75 mg aspirin intake | — |
Secondary
| Measure | Time frame |
|---|---|
| Platelet function by light transmission agregometry (LTA) 24 four hours after a 75 mg aspirin intake;, platelet production of TXB2 by lipidomic and platelet function by LTA at H2 and H12 after a75 mg aspirin intake, arterial thromboses identified in the CARMEN registry., Measurement of platelet TXB2 synthesis after platelet stimulation by arachidonic acid at H2 and H12 from a dose of 75 mg of AAS. 12-HETE produced by lymphoxygenase and quantified in the same mass spectrometry profile as TXB2 will also be taken into account. | — |
Countries
France
Outcome results
None listed