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Ergogenic effects of pseudoephedrine on edurance performance in relation to the determination of threshold values in urine and capillary and venous blood

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-513810-36-00
Acronym
ONZ-2023-0546
Enrollment
30
Registered
2025-05-08
Start date
2025-08-27
Completion date
Unknown
Last updated
2025-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers

Brief summary

Change in time trial duration (and average power output) when the placebo trial (0 mg) is compared to the trial with ingestion of 240 mg Pseudoephedrine

Detailed description

Changes in physiological parameters (cardiovascular, oxidative and metabolic) during the 90’ long cycling race simulation when the placebo trial (0 mg) is compared to the trial with ingestion of 120 mg Pseudoephedrine, Changes in physiological parameters (cardiovascular, oxidative and metabolic) during the 90’ long cycling race simulation when the placebo trial (0 mg) is compared to the trial with ingestion of 240 mg Pseudoephedrine, The upper limit of the 95% CI of the mean maximal measured blood/urine pseudoephedrine concentration after ingestion of 240 mg of pseudoephedrine for each sampling method (TASSO+, VAMS, DBS, Venapuncture and urine collection), Change in time trial duration (and average power output) when the half-dose trial (120 mg) is compared to the trial with ingestion of 0 mg Pseudoephedrine., Change in time trial duration (and average power output) when the half-dose trial (120 mg) is compared to the trial with ingestion of 240 mg Pseudoephedrine.

Interventions

DRUGVasocedine pseudoephedrine 60 mg
DRUGfilmomhulde tabletten

Sponsors

Universiteit Gent
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
Change in time trial duration (and average power output) when the placebo trial (0 mg) is compared to the trial with ingestion of 240 mg Pseudoephedrine

Secondary

MeasureTime frame
Changes in physiological parameters (cardiovascular, oxidative and metabolic) during the 90’ long cycling race simulation when the placebo trial (0 mg) is compared to the trial with ingestion of 120 mg Pseudoephedrine, Changes in physiological parameters (cardiovascular, oxidative and metabolic) during the 90’ long cycling race simulation when the placebo trial (0 mg) is compared to the trial with ingestion of 240 mg Pseudoephedrine, The upper limit of the 95% CI of the mean maximal measured blood/urine pseudoephedrine concentration after ingestion of 240 mg of pseudoephedrine for each sampling method (TASSO+, VAMS, DBS, Venapuncture and urine collection), Change in time trial duration (and average power output) when the half-dose trial (120 mg) is compared to the trial with ingestion of 0 mg Pseudoephedrine., Change in time trial duration (and average power output) when the half-dose trial (120 mg) is compared to the trial with ingestion of 240 mg Pseudoephedrine.

Countries

Belgium

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026