Glutamate infusion for prevention of Acute Kidney Injury in surgery for ischemic heart disease: (GLUTAMICS III = GLUTAmate for Metabolic Intervention in Coronary Surgery III)

Status

Not yet recruiting

Phases

Phase 3

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-513575-40-01

Enrollment

380

Registered

2024-09-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute kidney injury and heart failure after coronary artery bypass surgery in patients without diabetes

Brief summary

Incidence of postoperative acute kidney injury (AKI) measured as >= 50% postoperative increase of p-creatinine compared to preoperative value

Detailed description

Postoperative increase of p-NT-proBNP from the day before surgery to the third postoperative day

Interventions

DRUGSODIUM CHLORIDE

DRUGL-GLUTAMIC ACID

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative acute kidney injury (AKI) measured as >= 50% postoperative increase of p-creatinine compared to preoperative value	—

Secondary

Measure	Time frame
Postoperative increase of p-NT-proBNP from the day before surgery to the third postoperative day	—

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026