early syphilis
Conditions
Brief summary
A response will be defined as a four-fold decrease (2 dilutions) in titer in the non-treponemal assay (VDRL or RPR) at month 6 relative to the results of the assay performed before treatment. The two assays (before treatment and at month 6) should be performed in the same laboratory
Detailed description
Occurrence of SAEs in the two groups, Adherence to doxycycline, evaluated on the basis of a tablet count between weeks 1 and 2, during planned visits, Occurrence of other STDs in the two groups at month 6, Titer obtained in the non-treponemal assay (VDRL or RPR) at month 3 evolution
Interventions
DRUGcomprimé sécable
DRUGEXTENCILLINE 2
DRUG4 MUI
DRUGpoudre et solvant pour suspension injectable IM
Sponsors
Assistance Publique Hopitaux De Paris
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A response will be defined as a four-fold decrease (2 dilutions) in titer in the non-treponemal assay (VDRL or RPR) at month 6 relative to the results of the assay performed before treatment. The two assays (before treatment and at month 6) should be performed in the same laboratory | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of SAEs in the two groups, Adherence to doxycycline, evaluated on the basis of a tablet count between weeks 1 and 2, during planned visits, Occurrence of other STDs in the two groups at month 6, Titer obtained in the non-treponemal assay (VDRL or RPR) at month 3 evolution | — |
Countries
France
Outcome results
None listed