Guided by Light: Optimizing Surgical Excision of Oral Cancer Using Real-time Fluorescence Imaging

Status

Not yet recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-512824-13-01

Acronym

NL71347.078.20

Enrollment

Registered

2024-12-17

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral cancer

Brief summary

Rate of adequate (i.e. >5mm clear) tumor resection margins.

Detailed description

Sensitivity, specificity, positive and negative predictive values, Co-localization of FLI with immunohistochemistry on pathology slides, Percentage of extra tissue resection based on FLI-driven frozen sections, Operation time, FLI of lymph node metastases after neck dissection

Interventions

DRUGcRGD-ZW800-1

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Rate of adequate (i.e. >5mm clear) tumor resection margins.	—

Secondary

Measure	Time frame
Sensitivity, specificity, positive and negative predictive values, Co-localization of FLI with immunohistochemistry on pathology slides, Percentage of extra tissue resection based on FLI-driven frozen sections, Operation time, FLI of lymph node metastases after neck dissection	—

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026