Early triple-negative breast cancer (TNBC)
Conditions
Brief summary
Pathological complete response (pCR) in the primary tumor (ypT0/Tis) and affected lymph nodes (ypN0).
Detailed description
pCR (invasive and in-situ, only invasive, respectively) in the breast, pCR in lymph nodes, Pattern of non pCR, Radiological response according to RECIST v1.1, Radiological tumor response using two perpendicular diameters, EFS, Rate of breast conserving surgery (BCS) at the time of definitive surgery, Conversion of intention for mastectomy to BSC and axillary lymph node dissection (ALND) to sentinel lymph node dissection (SLND) or tailored axillary surgery (TAS) after treatment, Adverse events according to National Cancer institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) v5.0
Interventions
None listed
Sponsors
Swiss Cancer Institute
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathological complete response (pCR) in the primary tumor (ypT0/Tis) and affected lymph nodes (ypN0). | — |
Secondary
| Measure | Time frame |
|---|---|
| pCR (invasive and in-situ, only invasive, respectively) in the breast, pCR in lymph nodes, Pattern of non pCR, Radiological response according to RECIST v1.1, Radiological tumor response using two perpendicular diameters, EFS, Rate of breast conserving surgery (BCS) at the time of definitive surgery, Conversion of intention for mastectomy to BSC and axillary lymph node dissection (ALND) to sentinel lymph node dissection (SLND) or tailored axillary surgery (TAS) after treatment, Adverse events according to National Cancer institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) v5.0 | — |
Countries
France
Outcome results
None listed