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Efficacy, tolerability and preferences of per oral or subcutaneous methotrexate in patients with early rheumatoid arthritis – a randomised register based multicentre study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-512453-25-00
Acronym
MTXRA
Enrollment
212
Registered
2024-07-03
Start date
2022-04-28
Completion date
Unknown
Last updated
2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid arthritis

Brief summary

DAS28

Detailed description

Number of swollen joints, Number of tender joints, HAQ, VAS pain, VAS general health, VAS fatigue, Doctor's global assessment, Number of individuals remaining on the designated drug (drug retention) including number of individuals prescribed biologic treatment, Number of patient´s contact with any health care giver, All other medications, including corticosteroids, other csDMARDs, biologics, intraarticular injections as well as change in dosage or administration route of methotrexate, ESR, CRP, Number of AE, Patients preferences, EQ5D, Gutmicrobiota, Questions on diet and alcohol consumption

Interventions

DRUGMETHOTREXATE

Sponsors

Region Vaesterbotten
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
DAS28

Secondary

MeasureTime frame
Number of swollen joints, Number of tender joints, HAQ, VAS pain, VAS general health, VAS fatigue, Doctor's global assessment, Number of individuals remaining on the designated drug (drug retention) including number of individuals prescribed biologic treatment, Number of patient´s contact with any health care giver, All other medications, including corticosteroids, other csDMARDs, biologics, intraarticular injections as well as change in dosage or administration route of methotrexate, ESR, CRP, Number of AE, Patients preferences, EQ5D, Gutmicrobiota, Questions on diet and alcohol consumption

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026