The GOBLET trial: A clinical trial on GOblet cell density after Benzalkonium chloride and preservative-free Latanoprost Eye drop Treatment

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2024-512275-12-00

Acronym

WP3

Enrollment

Registered

2024-03-19

Start date

Unknown

Completion date

2025-08-04

Last updated

2024-10-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular hypertension, Primary open angle glaucoma

Brief summary

change in Goblet cell density

Detailed description

Change in intraocular pressure, change in oxford score of fluorescein and lissamine staining of cornea and conjunctiva, change in conentration of mucin and cytokine concentration in tear film, Change in OSDI score

Interventions

DRUGMonoprost

DRUGøjendråber

DRUGopløsning

DRUGXalatan

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
change in Goblet cell density	—

Secondary

Measure	Time frame
Change in intraocular pressure, change in oxford score of fluorescein and lissamine staining of cornea and conjunctiva, change in conentration of mucin and cytokine concentration in tear film, Change in OSDI score	—

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026