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Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost-effective treatment of refractory angina. A phase II randomized, double-blinded, placebo-controlled study.

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-512255-20-00
Acronym
RGH201
Enrollment
39
Registered
2024-05-29
Start date
Unknown
Completion date
2024-05-31
Last updated
2024-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost- effective treatment of refractory angina. A phase II randomized, double-blinded, placebo-controlled study.

Brief summary

Improvement of functional capacity using 6-minute walking test, Improvement of symptoms assessed by Canadian Cardiovascular Society (CCS) class

Detailed description

Improvement of functional capacity using 6-minute walking test, Improvement of symptoms assessed by Canadian Cardiovascular Society (CCS) class, Increase in myocardial perfusion

Interventions

DRUGAdsVEGF-D Delta N Delta C
DRUGPlacebo to AdsVEGF-D Delta N Delta C test product

Sponsors

Pohjois-Savon hyvinvointialue
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Improvement of functional capacity using 6-minute walking test, Improvement of symptoms assessed by Canadian Cardiovascular Society (CCS) class

Secondary

MeasureTime frame
Improvement of functional capacity using 6-minute walking test, Improvement of symptoms assessed by Canadian Cardiovascular Society (CCS) class, Increase in myocardial perfusion

Countries

Denmark, Finland

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026