Patients requiring emergency abdominal or body CT with eGFR 15-45 ml/min/1.73 m2. The eGFR is calculated from the last available plasma creatinine value taken maximum 24 hours before randomisation.
Conditions
Brief summary
A composite outcome that combines all-cause mortality or renal replacement therapy within 90 days of contrast medium exposure
Detailed description
The most severe acute kidney injury (AKI) grade defined by KDIGO classification on plasma creatinine within 72 hours after CT, Any organ dysfunction defined by at least 2 mSOFA (modified Sequential Organ Failure Assessment) points excluding central nervous system 48 hours after CT, Alive and hospital-free days within 90 days after CT, Time from imaging to definitive treatment during hospital stay
Interventions
Sponsors
University Of Helsinki
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A composite outcome that combines all-cause mortality or renal replacement therapy within 90 days of contrast medium exposure | — |
Secondary
| Measure | Time frame |
|---|---|
| The most severe acute kidney injury (AKI) grade defined by KDIGO classification on plasma creatinine within 72 hours after CT, Any organ dysfunction defined by at least 2 mSOFA (modified Sequential Organ Failure Assessment) points excluding central nervous system 48 hours after CT, Alive and hospital-free days within 90 days after CT, Time from imaging to definitive treatment during hospital stay | — |
Countries
Finland, Norway
Outcome results
None listed