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The headache-inducing effects of sildenafil in men and women with episodic migraine without aura.

Status
Completed
Phases
Phase 1Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-512014-17-02
Enrollment
27
Registered
2024-08-03
Start date
2024-11-01
Completion date
2025-07-10
Last updated
2024-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine without aura

Brief summary

Difference in the occurrence of migraine-like attacks in sildenafil- and placebo-treated men with migraine without aura., Difference in the occurrence of migraine-like attacks in sildenafil-treated men and women with migraine without aura.

Detailed description

Difference in the occurrence of headache in sildenafil- and placebo-treated men with migraine without aura., Difference in heart rate and mean arterial pressure (MAP) between sildenafil- and placebo-treated men with migraine without aura, Difference in the incidence of adverse events between sildenafil- and placebo-treated men with migraine without aura

Interventions

DRUGSildenafil Orion 100 mg filmdragerade tabletter
DRUGfilmomhulde tabletten

Sponsors

Syddansk Universitet (University of Southern Denmark)
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
Difference in the occurrence of migraine-like attacks in sildenafil- and placebo-treated men with migraine without aura., Difference in the occurrence of migraine-like attacks in sildenafil-treated men and women with migraine without aura.

Secondary

MeasureTime frame
Difference in the occurrence of headache in sildenafil- and placebo-treated men with migraine without aura., Difference in heart rate and mean arterial pressure (MAP) between sildenafil- and placebo-treated men with migraine without aura, Difference in the incidence of adverse events between sildenafil- and placebo-treated men with migraine without aura

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 7, 2026