ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI)
Conditions
Brief summary
The primary endpoint is the incidence of high platelet reactivity (HPR), defined as a measured closure time (CT) ≤ 106 seconds, at predefined time points after cangrelor interruption, assessed by platelet function analyzer (PFA)-200 P2Y test, in Early Group compared to Delayed Group.
Detailed description
- Difference in mean measured CT. - Incidence of major adverse cardiovascular events (MACE) within 30 days. - Mortality within 30 days. - Incidence of stent thrombosis within 30 days. - Incidence of unplanned revascularization within 30 days. - Incidence of peri-procedural infarction. - Bleeding events according to the BARC criteria.
Interventions
Sponsors
Azienda Ospedaliero-Universitaria Maggiore Della Carita
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the incidence of high platelet reactivity (HPR), defined as a measured closure time (CT) ≤ 106 seconds, at predefined time points after cangrelor interruption, assessed by platelet function analyzer (PFA)-200 P2Y test, in Early Group compared to Delayed Group. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Difference in mean measured CT. - Incidence of major adverse cardiovascular events (MACE) within 30 days. - Mortality within 30 days. - Incidence of stent thrombosis within 30 days. - Incidence of unplanned revascularization within 30 days. - Incidence of peri-procedural infarction. - Bleeding events according to the BARC criteria. | — |
Countries
Italy
Outcome results
None listed