Skip to content

A Phase 2 Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of ARO-APOC3 in Adults with Dyslipidemia

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-511331-96-00
Acronym
AROAPOC3-2003
Enrollment
178
Registered
2024-07-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mixed Dyslipidemia

Brief summary

Subject incidence of treatment-emergent adverse events (TEAEs)

Detailed description

Change and percent change from baseline over time in fasting TG (triglyceride), Change and percent change from baseline over time in apolipoprotein (Apo)C-III, Change and percent change from baseline over time in fasting non-high-density lipoprotein cholesterol (non-HDL-C), Change and percent change from baseline over time in fasting HDL-C, Change and percent change from baseline over time in fasting total apolipoprotein B (ApoB), Change and percent change from baseline over time in fasting LDL-C (low-density lipoprotein cholesterol) using ultracentrifugation

Interventions

Sponsors

Arrowhead Pharmaceuticals Inc.
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Subject incidence of treatment-emergent adverse events (TEAEs)

Secondary

MeasureTime frame
Change and percent change from baseline over time in fasting TG (triglyceride), Change and percent change from baseline over time in apolipoprotein (Apo)C-III, Change and percent change from baseline over time in fasting non-high-density lipoprotein cholesterol (non-HDL-C), Change and percent change from baseline over time in fasting HDL-C, Change and percent change from baseline over time in fasting total apolipoprotein B (ApoB), Change and percent change from baseline over time in fasting LDL-C (low-density lipoprotein cholesterol) using ultracentrifugation

Countries

Hungary, Netherlands, Poland

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026