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A clinical phase IV trial to examine cellular and humoral immunity against measles and chickenpox in children and adolescents 0-18 years in childhood cancer.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-511182-10-01
Acronym
immvzmpr1
Enrollment
160
Registered
2024-09-27
Start date
2025-05-22
Completion date
Unknown
Last updated
2024-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric cancer

Brief summary

Difference in VZ IgG antibody levels before and after revaccination against chickenpox, Difference in measles IgG antibody level before and after revaccination against measles

Detailed description

Percentage of patients with immunity against chickenpox and measles before and after treatment measured in IgG, Changes in cellmediated immunity (CMI) against chickenpox and measles before and after revaccination. Comparisons with a healthy control group., Differences in antibody levels and CMI between various diagnostic groups (leukemias, solid tumors), different age groups, low- vs. high-intensity treatment, and pre-immune versus non-immune groups

Interventions

Sponsors

Vaestra Goetalandsregionen
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
0 Years to 17 Years

Design outcomes

Primary

MeasureTime frame
Difference in VZ IgG antibody levels before and after revaccination against chickenpox, Difference in measles IgG antibody level before and after revaccination against measles

Secondary

MeasureTime frame
Percentage of patients with immunity against chickenpox and measles before and after treatment measured in IgG, Changes in cellmediated immunity (CMI) against chickenpox and measles before and after revaccination. Comparisons with a healthy control group., Differences in antibody levels and CMI between various diagnostic groups (leukemias, solid tumors), different age groups, low- vs. high-intensity treatment, and pre-immune versus non-immune groups

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026