Advancing the quality of treatment and care for acute agitation in emergency psychiatry

Conditions

acute agitation

Brief summary

PANSS Excited Component (PEC) score at 60 minutes post-dose (change from pre- to post-dose)

Detailed description

The earliest time where a statistically significant difference in agitation is apparent as measured by change from baseline PEC score (change from pre- to post-dose PEC score at 30, 60, 90, and 120 minutes), Proportion tranquillized or asleep (measured as ≤4 on the BARS**) by 30, 60, 90, and 120 minutes post-dose, Proportion physically restrained from administration to 12 hours post-dose, Proportion mechanically restrained from administration to 12 hours post-dose, Proportion given rescue medication 4-12 hours post-dose, Patient-reported satisfaction measured using 4 items from the Treatment Satisfaction Questionnaire for Medication II

Related papers

No related papers found yet.

Interventions

DRUGLorazepam Orion 1 mg tabletter

DRUGMidazolam Medical Valley 10 mg munhålelösning

DRUGIgalmi

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Design outcomes

Primary

Measure	Time frame
PANSS Excited Component (PEC) score at 60 minutes post-dose (change from pre- to post-dose)	—

Secondary

Measure	Time frame
The earliest time where a statistically significant difference in agitation is apparent as measured by change from baseline PEC score (change from pre- to post-dose PEC score at 30, 60, 90, and 120 minutes), Proportion tranquillized or asleep (measured as ≤4 on the BARS**) by 30, 60, 90, and 120 minutes post-dose, Proportion physically restrained from administration to 12 hours post-dose, Proportion mechanically restrained from administration to 12 hours post-dose, Proportion given rescue medication 4-12 hours post-dose, Patient-reported satisfaction measured using 4 items from the Treatment Satisfaction Questionnaire for Medication II	—

Measure

Time frame

The earliest time where a statistically significant difference in agitation is apparent as measured by change from baseline PEC score (change from pre- to post-dose PEC score at 30, 60, 90, and 120 minutes), Proportion tranquillized or asleep (measured as ≤4 on the BARS**) by 30, 60, 90, and 120 minutes post-dose, Proportion physically restrained from administration to 12 hours post-dose, Proportion mechanically restrained from administration to 12 hours post-dose, Proportion given rescue medication 4-12 hours post-dose, Patient-reported satisfaction measured using 4 items from the Treatment Satisfaction Questionnaire for Medication II

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Countries

Denmark

Outcome results

None listed