Skip to content

Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial: the WATERLAND trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-509879-16-00
Acronym
WATERLAND
Enrollment
100
Registered
2024-01-11
Start date
Unknown
Completion date
2024-08-30
Last updated
2024-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pancreatitis

Brief summary

The primary outcome will be moderately severe to severe AP, according to the RAC. (Atlanta classification) within the first 30 days after randomization.

Detailed description

Local complications (specific complications will be also recorded) Necrotizing pancreatitis SIRS Number of SIRS criteria PAN-PROMISE symptom scale Time to oral refeeding Invasive treatment Nutritional support Intensive care unit admission Exacerbation of coexisting condition Any organ failure Persistent organ failure Shock Respiratory failure Kidney failure Death Hospital stay C-reactive protein

Interventions

DRUGFreeflex Ringer Lactato solución para perfusión

Sponsors

Hospital General Universitario Dr. Balmis
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
The primary outcome will be moderately severe to severe AP, according to the RAC. (Atlanta classification) within the first 30 days after randomization.

Secondary

MeasureTime frame
Local complications (specific complications will be also recorded) Necrotizing pancreatitis SIRS Number of SIRS criteria PAN-PROMISE symptom scale Time to oral refeeding Invasive treatment Nutritional support Intensive care unit admission Exacerbation of coexisting condition Any organ failure Persistent organ failure Shock Respiratory failure Kidney failure Death Hospital stay C-reactive protein

Countries

France, Spain

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026