General healthy elderly with stable medical conditions
Conditions
Brief summary
Changes in serum bone formation marker P1NP
Detailed description
Changes in serum bone resorption marker CTX, Changes in areal BMD at the lumbar spine, total hip and femoral neck measured by DXA scanning, Changes in volumetric BMD, bone microstructures and estimated strength at distal tibia and radius (HRpQT), Changes in muscle function, power and strength for upper and lower extremities will be assessed using a standard hydraulic hand dynamometer, the 30-second sit-to-stand test (RSS), respectively and gait speed., Changes in health-related quality of life assessment (SF-12 questionnaire)
Interventions
Sponsors
Eligibility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in serum bone formation marker P1NP | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in serum bone resorption marker CTX, Changes in areal BMD at the lumbar spine, total hip and femoral neck measured by DXA scanning, Changes in volumetric BMD, bone microstructures and estimated strength at distal tibia and radius (HRpQT), Changes in muscle function, power and strength for upper and lower extremities will be assessed using a standard hydraulic hand dynamometer, the 30-second sit-to-stand test (RSS), respectively and gait speed., Changes in health-related quality of life assessment (SF-12 questionnaire) | — |
Countries
Denmark