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A Phase 1 first in human study evaluating safety, pharmacokinetics and efficacy of ABBV-400 as monotherapy and in combination with bevacizumab in adult subjects with advanced solid tumors

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-509335-60-00
Acronym
M21-404
Enrollment
177
Registered
2024-07-11
Start date
2023-02-23
Completion date
Unknown
Last updated
2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced solid tumors including (but not limited to), and renal cell carcinoma (RCC), colorectal cancer (CRC), gastric/gastroesophageal junction adenocarcinoma (GEA), head and neck squamous cell carcinoma (HNSCC), non-small cell lung cancer (NSCLC)

Interventions

None listed

Sponsors

AbbVie Deutschland GmbH & Co. KG
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Countries

France, Germany, Poland, Spain

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026