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An Open-Label, Multicenter, Long-term Extension Study of Treatment With Tislelizumab, Pamiparib, and Other Investigational Agents in Patients With Advanced Malignancies

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-508883-31-00
Acronym
BGB-A317-290-LTE1
Enrollment
21
Registered
2024-03-08
Start date
2021-02-23
Completion date
Unknown
Last updated
2026-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Solid tumors and hamatological malignancies

Brief summary

Safety as assessed by incidence of all AEs of special interest, Grade 3, 4, or 5 AEs, Grade 2 AEs that affect vital organs (eg, heart, liver, brain, lung, kidney), nonserious AEs that lead to dose modification or drug discontinuation or withdrawal from the trial, and SAEs of any severity.

Detailed description

Overall survival defined as the time from start of treatment in parent study (or randomization date for a randomized study) until the date of death from any cause.

Interventions

DRUGPamiparib
DRUGTislelizumab

Sponsors

BeOne Medicines AG
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Safety as assessed by incidence of all AEs of special interest, Grade 3, 4, or 5 AEs, Grade 2 AEs that affect vital organs (eg, heart, liver, brain, lung, kidney), nonserious AEs that lead to dose modification or drug discontinuation or withdrawal from the trial, and SAEs of any severity.

Secondary

MeasureTime frame
Overall survival defined as the time from start of treatment in parent study (or randomization date for a randomized study) until the date of death from any cause.

Countries

France, Italy, Poland

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026