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Understanding the Neurobiology of Pharmacologically-induced Acute Stress on Ethical Decisions

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-508731-31-01
Enrollment
100
Registered
2024-04-25
Start date
2024-07-18
Completion date
2025-06-30
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mimic an acute stress response in humans.

Brief summary

The number of utilitarian, deontological, and compromise choices made in a behavioural task measuring moral judgement., The number of violations in rationality when making moral decisions.

Detailed description

The total score of the forward, backward, and sequencing digit span of the Digit Span Task, an assessment of working memory., The stop signal reaction time of the Stop Signal Task, assessment of impulse control., The mean adjusted amount of button clicks and total number of exploded balloons for each risk condition in the Balloon Analogue Risk Taking task, assessment for risk-taking.

Interventions

DRUGCELLULOSE
DRUGYOCORAL 5 mg tabletten
DRUGHydrocortison Teva 10 mg
DRUGfilmomhulde tabletten

Sponsors

Universitair Medisch Centrum Utrecht
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Design outcomes

Primary

MeasureTime frame
The number of utilitarian, deontological, and compromise choices made in a behavioural task measuring moral judgement., The number of violations in rationality when making moral decisions.

Secondary

MeasureTime frame
The total score of the forward, backward, and sequencing digit span of the Digit Span Task, an assessment of working memory., The stop signal reaction time of the Stop Signal Task, assessment of impulse control., The mean adjusted amount of button clicks and total number of exploded balloons for each risk condition in the Balloon Analogue Risk Taking task, assessment for risk-taking.

Countries

Netherlands

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026