68Gallium-FAPI PET/CT imaging in Chronic inflammatory and fibrotic diseases (PARADISE study)

Inflammatory disorders

Binding intensity in TEP, measured by the Standardized uptake value (SUV) max.

To meet the first secondary objective: - Measurement of fixation intensity in PET and measurement of pathology-specific reference score (if applicable)., To meet the second secondary objective: - Measurement of fixation intensity in PET and measurement of other pathology-specific assessment scores (if applicable), To meet the third secondary objective: - Measurement of PET fixation intensity and measurement of pathology-specific biomarkers (if applicable), To meet the fourth secondary objective: - Measurement of PET fixation intensity and measurement of pathology-specific functional parameters (if applicable), To meet the fifth secondary objective: - Measurement of PET fixation intensity and assessment of pathology-specific imaging characteristics (if applicable), To meet the sixth secondary objective: - Measurement of [68Ga] Ga-FAPI PET/CT fixation intensity and measurement of [18F] F-FDG PET/CT fixation intensity at M0, To address the seventh secondary objective: - Evaluation of [68Ga] Ga-FAPI tracer uptake kinetics in PET according to different pathologies and their phenotypic characteristics., To meet cross-cutting secondary objectives: - Measurement of [68Ga] Ga-FAPI PET/CT fixation intensity and measurement of SF-36 questionnaire score, - Measurement of [68Ga] Ga-FAPI PET/CT fixation intensity and measurement of global disease assessment.

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France