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Intravenous lidocaine and post operative recovery after liver surgery – a randomized double blinded study

Status
Completed
Phases
Phase 2Phase 3
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-508173-90-00
Enrollment
124
Registered
2024-09-30
Start date
2021-11-15
Completion date
2025-12-06
Last updated
2024-09-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with liver tumours that have liver surgery performed

Brief summary

Total opioid consumption the first 24 hours. (mg morfin equivalents)

Detailed description

Total opioid consumption the first 48 hours. (mg morfin equivalents), Postoperative intensity of pain, NRS (numerical rating scale), Complications (Clavien-Dindo), Total Intravenous Opioid consumption in the first 24 hours, and after the first 48 hours (mg morfin equivalents), Total opioid consumption by day 3, 4, 5 (mg morfin equivalenter), Time to flatus, Time to bowel movement, Nausea, vomiting, Length of stay in hospital, Mortality, Lidocaine- and MEGX-koncentration in blood immediately after induction of anestesia , 30 minutes after resection and at the end of infusion., QoR-40, adverse events

Interventions

DRUGLIDOCAINE
DRUGSODIUM CHLORIDE

Sponsors

Region Skane
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
Total opioid consumption the first 24 hours. (mg morfin equivalents)

Secondary

MeasureTime frame
Total opioid consumption the first 48 hours. (mg morfin equivalents), Postoperative intensity of pain, NRS (numerical rating scale), Complications (Clavien-Dindo), Total Intravenous Opioid consumption in the first 24 hours, and after the first 48 hours (mg morfin equivalents), Total opioid consumption by day 3, 4, 5 (mg morfin equivalenter), Time to flatus, Time to bowel movement, Nausea, vomiting, Length of stay in hospital, Mortality, Lidocaine- and MEGX-koncentration in blood immediately after induction of anestesia , 30 minutes after resection and at the end of infusion., QoR-40, adverse events

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026