Patients with chronic kidney disease stage 3b to 4
Conditions
Brief summary
The difference of serum potassium at baseline and after six weeks of treatment with potassium enriched diet (non-inferiority design) compared to the control group. With an intention to treat analysis.
Detailed description
Ambulatory blood pressure, 24 hours albuminuria, urinary potassium and sodium excretion, Plasma bicarbonate, Quality of life, using SF36 questionnaire, Effect on stool (assessed with Bristol Stool Chart), Difference in serum potassium one week after start of study (SCZ free period), Per protocol analysis of difference in serum potassium after six week (end of study), Incidence of severe hyperkalemia (serum potassium above 6.5 mmol/l or above 6.0 with ECG features of hyperkalemia)
Interventions
Sponsors
Academisch Ziekenhuis Leiden
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference of serum potassium at baseline and after six weeks of treatment with potassium enriched diet (non-inferiority design) compared to the control group. With an intention to treat analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ambulatory blood pressure, 24 hours albuminuria, urinary potassium and sodium excretion, Plasma bicarbonate, Quality of life, using SF36 questionnaire, Effect on stool (assessed with Bristol Stool Chart), Difference in serum potassium one week after start of study (SCZ free period), Per protocol analysis of difference in serum potassium after six week (end of study), Incidence of severe hyperkalemia (serum potassium above 6.5 mmol/l or above 6.0 with ECG features of hyperkalemia) | — |
Countries
Netherlands
Outcome results
None listed