Healthy aging, Sarcopenia, Anabolic resistance, Anti-Doping
Conditions
Brief summary
Mean differences in fat-free mass, muscle size, and muscle fibre types cross-sectional area (CSA) between placebo or testosterone groups +/- resistance training, measured by DEXA, ultrasound, and muscle biopsies .
Detailed description
Differences in myonuclear accretion and permanence and/or the retainment of imprinted epigenetic signatures (DNA methylation) and corresponding gene expression in skeletal muscle between placebo or testosterone groups +/- resistance training., Mean differences in strength, velocity and power between placebo and testosterone groups +/- resistance training, measured by with ultrasound, Keiser leg press machine and IMVC using isokinetic dynamometry
Interventions
DRUGNebido 1000 mg/4 ml injeksjonsvæske
DRUGoppløsning
Sponsors
Norges Idrettshoegskole
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean differences in fat-free mass, muscle size, and muscle fibre types cross-sectional area (CSA) between placebo or testosterone groups +/- resistance training, measured by DEXA, ultrasound, and muscle biopsies . | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in myonuclear accretion and permanence and/or the retainment of imprinted epigenetic signatures (DNA methylation) and corresponding gene expression in skeletal muscle between placebo or testosterone groups +/- resistance training., Mean differences in strength, velocity and power between placebo and testosterone groups +/- resistance training, measured by with ultrasound, Keiser leg press machine and IMVC using isokinetic dynamometry | — |
Countries
Norway
Outcome results
None listed