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Accelerated treatment of infectious endocarditis

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-507652-76-00
Enrollment
50
Registered
2024-10-17
Start date
2022-01-02
Completion date
Unknown
Last updated
2024-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious endocarditis

Brief summary

The primary outcome is combined and consists of the following events within 6 months after randomization: a. Death. b. Septic embolization. c. Bacteraemia with the same microorganism. d. Heart surgery not planned at the time of randomization.

Detailed description

a. Expenses related to hospital care and other treatment of the condition. b. Length of hospital stay. c. Length of antibiotic tratment. d. Complications related to intravenous access.

Interventions

DRUGlösning
DRUGMeropenem Fresenius Kabi 1 g pulver till injektionsvätska eller infusionsvätska
DRUGCeftriaxon Fresenius Kabi 2 g pulver till infusionsvätska
DRUGBensylpenicillin Meda 3 g pulver till injektions/infusionsvätska
DRUGDoktacillin 1g respektive 2 g pulver till injektions/infusionsvätska
DRUGCefotaxim Stragen 1 g pulver till injektions- och infusionsvätska
DRUGCubicin 350 mg powder for solution for injection or infusion

Sponsors

Region Skane
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
The primary outcome is combined and consists of the following events within 6 months after randomization: a. Death. b. Septic embolization. c. Bacteraemia with the same microorganism. d. Heart surgery not planned at the time of randomization.

Secondary

MeasureTime frame
a. Expenses related to hospital care and other treatment of the condition. b. Length of hospital stay. c. Length of antibiotic tratment. d. Complications related to intravenous access.

Countries

Sweden

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026