Effect of low-dose arginine-vasopressin supplementation on post-transplant Acute Kidney Injury after liver transplantation - AVENIR Trial

Conditions

Liver transplantation, Acute Kidney Injury

Brief summary

Stages of AKI according to AKI Network criteria (KDIGO score) during the first 7 postoperative days

Detailed description

The number of packed red blood cells and fresh frozen plasma transfused intraoperatively and during the first 12 hours postoperatively, The need for renal replacement for replacement therapy (RRT) in ICU, Average intraoperative norepinephrine concentrations, Average intraoperative concentrations of other vasopressors and inotropes (Adrenalin, Dobutamine), Number of platelets transfused intraoperatively and during the first 12 hours postoperatively, Amount of vascular filling solutions intraoperatively and during the first 12 hours postoperatively, Sequential Organ Failure Assessment (score SOFA) on the third postoperative day, Number of days alive outside intensive care unit during the 30 day post-operation, Mortality at 30 days

Related papers

No related papers found yet.

Interventions

DRUGREVERPLEG 40 U.I./2 mL

DRUGsolution à diluer pour perfusion

DRUGNORADRENALINE VIATRIS 2 mg/ml SANS SULFITES

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Stages of AKI according to AKI Network criteria (KDIGO score) during the first 7 postoperative days	—

Secondary

Measure	Time frame
The number of packed red blood cells and fresh frozen plasma transfused intraoperatively and during the first 12 hours postoperatively, The need for renal replacement for replacement therapy (RRT) in ICU, Average intraoperative norepinephrine concentrations, Average intraoperative concentrations of other vasopressors and inotropes (Adrenalin, Dobutamine), Number of platelets transfused intraoperatively and during the first 12 hours postoperatively, Amount of vascular filling solutions intraoperatively and during the first 12 hours postoperatively, Sequential Organ Failure Assessment (score SOFA) on the third postoperative day, Number of days alive outside intensive care unit during the 30 day post-operation, Mortality at 30 days	—

Measure

Time frame

The number of packed red blood cells and fresh frozen plasma transfused intraoperatively and during the first 12 hours postoperatively, The need for renal replacement for replacement therapy (RRT) in ICU, Average intraoperative norepinephrine concentrations, Average intraoperative concentrations of other vasopressors and inotropes (Adrenalin, Dobutamine), Number of platelets transfused intraoperatively and during the first 12 hours postoperatively, Amount of vascular filling solutions intraoperatively and during the first 12 hours postoperatively, Sequential Organ Failure Assessment (score SOFA) on the third postoperative day, Number of days alive outside intensive care unit during the 30 day post-operation, Mortality at 30 days

—

Countries

France

Outcome results

None listed