Perioperative methadone compared to placebo in elderly hip fracture patients – a randomized controlled trial. Phase two of the MetaHip trial

Status

Completed

Phases

Phase 3Phase 4

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2023-506252-24-00

Enrollment

130

Registered

2023-10-02

Start date

2023-11-07

Completion date

2025-02-21

Last updated

2023-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip fractures

Brief summary

Daily consumption of opioids

Detailed description

Pain, Standing up, Mobility, Nausea or vomiting, Time to discharge, Need for an antidote, Delirium, Constipation

Interventions

DRUGMETHADONE

DRUGNatriumklorid 9 mg/ml "Fresenius Kabi"

DRUGsolvens til parenteralt brug

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Daily consumption of opioids	—

Secondary

Measure	Time frame
Pain, Standing up, Mobility, Nausea or vomiting, Time to discharge, Need for an antidote, Delirium, Constipation	—

Countries

Denmark

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 6, 2026