Pregnant women with singleton pregnancies hospitalized for threatened late miscarriage with intact membranes
Conditions
Brief summary
Composite criterion combining late miscarriage, perinatal mortality, and/or severe neonatal morbidity occurring before hospital discharge, including: 1-Late miscarriage, Perinatal mortality, Bronchopulmonary dysplasia, Sepsis proven by blood culture, Intraventricular hemorrhage ≥ Grade 3, Periventricular leukomalacia ≥ Grade 2, Necrotizing enterocolitis at stage ≥ 2 according to Bell's classification
Detailed description
Each item of the composite criterion: 1-Neonatal mortality and late miscarriage, Bronchopulmonary dysplasia according to international recommendations (described by Jobe and Bancalari), diagnosed at discharge or at a corrected age of 36 6/7 weeks of gestation., Sepsis proven by culture, diagnosed by a combination of clinical signs and a positive blood culture, Intraventricular hemorrhage ≥ Grade 3 and/or periventricular leukomalacia, diagnosed by repeated transfontanellar ultrasounds (according to the classification of Vries and Ment), Necrotizing enterocolitis ≥ Stage 2, using Bell's classification.
Interventions
DRUGCEFTRIAXONE VIATRIS 1 g
DRUGpoudre pour solution injectable
DRUGClarithromycine EG 500 mg comprimés pelliculés
DRUGMÉTRONIDAZOLE ARROW 500 mg
Sponsors
Assistance Publique Hopitaux De Paris
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite criterion combining late miscarriage, perinatal mortality, and/or severe neonatal morbidity occurring before hospital discharge, including: 1-Late miscarriage, Perinatal mortality, Bronchopulmonary dysplasia, Sepsis proven by blood culture, Intraventricular hemorrhage ≥ Grade 3, Periventricular leukomalacia ≥ Grade 2, Necrotizing enterocolitis at stage ≥ 2 according to Bell's classification | — |
Secondary
| Measure | Time frame |
|---|---|
| Each item of the composite criterion: 1-Neonatal mortality and late miscarriage, Bronchopulmonary dysplasia according to international recommendations (described by Jobe and Bancalari), diagnosed at discharge or at a corrected age of 36 6/7 weeks of gestation., Sepsis proven by culture, diagnosed by a combination of clinical signs and a positive blood culture, Intraventricular hemorrhage ≥ Grade 3 and/or periventricular leukomalacia, diagnosed by repeated transfontanellar ultrasounds (according to the classification of Vries and Ment), Necrotizing enterocolitis ≥ Stage 2, using Bell's classification. | — |
Countries
France
Outcome results
None listed