Biochemical recurrence after prostate cancer surgery
Conditions
Brief summary
Primary PSA progression free survival (PFS) defined as documented biological progression: No response to SRT: the PSA value 3 months after completion of SRT is ≥ 0.1 ng/mL higher than the PSA value just before radiotherapy. Progression after initial response to SRT: Two rising PSA values ≥ 0.1 ng/mL after completion of radiotherapy, with the last value ≥ 0.2 ng/mL.
Detailed description
Time to metastasis, Prostate cancer specific survival, Overall survival, Time to secondary treatment: Time from randomization to start of secondary treatment, usually hormonal treatment, Quality of life: All patients fill in PSMA-PROM, a study modified quality of life questionnaire developed by the National PCa Register at baseline and 6, 12, 36, and 60 months after completed treatment.
Interventions
Sponsors
Karolinska University Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary PSA progression free survival (PFS) defined as documented biological progression: No response to SRT: the PSA value 3 months after completion of SRT is ≥ 0.1 ng/mL higher than the PSA value just before radiotherapy. Progression after initial response to SRT: Two rising PSA values ≥ 0.1 ng/mL after completion of radiotherapy, with the last value ≥ 0.2 ng/mL. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to metastasis, Prostate cancer specific survival, Overall survival, Time to secondary treatment: Time from randomization to start of secondary treatment, usually hormonal treatment, Quality of life: All patients fill in PSMA-PROM, a study modified quality of life questionnaire developed by the National PCa Register at baseline and 6, 12, 36, and 60 months after completed treatment. | — |
Countries
Sweden
Outcome results
None listed