An Open-Label, Multicenter Switch Study Evaluating Changes in Blood Pressure in Participants With Narcolepsy Switching From High-Sodium Oxybate to XYWAV

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2023-504892-25-00

Enrollment

Registered

2023-11-14

Start date

2024-06-14

Completion date

2025-03-10

Last updated

2025-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Narcolepsy

Brief summary

Change from baseline to EOT Visit on the 24-hour average SBP (mm Hg)

Detailed description

Change from baseline to EOT Visit on the daytime average SBP (mm Hg), Change from baseline to EOT Visit on the seated resting average SBP (mm Hg), Change from baseline to EOT Visit on the nighttime average SBP (mm Hg)

Interventions

DRUGJZP258

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Change from baseline to EOT Visit on the 24-hour average SBP (mm Hg)	—

Secondary

Measure	Time frame
Change from baseline to EOT Visit on the daytime average SBP (mm Hg), Change from baseline to EOT Visit on the seated resting average SBP (mm Hg), Change from baseline to EOT Visit on the nighttime average SBP (mm Hg)	—

Countries

Belgium, Czechia, France, Italy, Spain

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026