Effects of single-pill combination of telmisartan/amlodipine and telmisartan/amlodipine/hydrochlorothiazide on 24-hour blood pressure (BP) reduction, 24-h BP variability and office BP control in patients with arterial hypertension

Conditions

Arterial hypertension

Brief summary

Mean absolute change of 24-hour SBP after 16 weeks of treatment (from baseline to Visit 7) with TIMP.

Detailed description

Mean change in average real variability of 24-hour SBP (ARVs) and mean change in average real variability of 24-hour DBP (ARVd) after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute change of 24-hour DBP after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute and relative changes of office SBP and DBP after 4, 8, 12 and 16 weeks of treatment (from baseline to Visit 3, Visit 4, Visit 5 and Visit 7, respectively) with TIMP., Mean absolute change of the calculated central SBP (cSBP) and calculated central DBP (cDBP) after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean SI after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute changes of 24-hour SBP, separately in groups of dipping, extreme dipping and non-dipping patients after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute change of pulse wave velocity (PWV) after 16 weeks of treatment (from baseline to Visit 7) with TIMP.

Related papers

No related papers found yet.

Interventions

DRUGTelmisartan/Amlodipine/Hydrochlorothiazide

DRUGTeldipin

DRUG80 mg + 5 mg

DRUGtabletki

DRUGTamloset 40 mg/5 mg tabletta

DRUGTamloset 80 mg/10 mg tabletta

DRUGTelassmo 80 mg/10 mg tablete

DRUGTamloset 80 mg/5 mg tabletta

DRUG80 mg + 10 mg

DRUGTelassmo 40 mg/5 mg tablete

DRUG40 mg + 5 mg

DRUGTelassmo 80 mg/5 mg tablete

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Mean absolute change of 24-hour SBP after 16 weeks of treatment (from baseline to Visit 7) with TIMP.	—

Secondary

Measure	Time frame
Mean change in average real variability of 24-hour SBP (ARVs) and mean change in average real variability of 24-hour DBP (ARVd) after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute change of 24-hour DBP after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute and relative changes of office SBP and DBP after 4, 8, 12 and 16 weeks of treatment (from baseline to Visit 3, Visit 4, Visit 5 and Visit 7, respectively) with TIMP., Mean absolute change of the calculated central SBP (cSBP) and calculated central DBP (cDBP) after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean SI after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute changes of 24-hour SBP, separately in groups of dipping, extreme dipping and non-dipping patients after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute change of pulse wave velocity (PWV) after 16 weeks of treatment (from baseline to Visit 7) wit	—

Measure

Time frame

Mean change in average real variability of 24-hour SBP (ARVs) and mean change in average real variability of 24-hour DBP (ARVd) after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute change of 24-hour DBP after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute and relative changes of office SBP and DBP after 4, 8, 12 and 16 weeks of treatment (from baseline to Visit 3, Visit 4, Visit 5 and Visit 7, respectively) with TIMP., Mean absolute change of the calculated central SBP (cSBP) and calculated central DBP (cDBP) after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean SI after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute changes of 24-hour SBP, separately in groups of dipping, extreme dipping and non-dipping patients after 16 weeks of treatment (from baseline to Visit 7) with TIMP., Mean absolute change of pulse wave velocity (PWV) after 16 weeks of treatment (from baseline to Visit 7) wit

—

Countries

Hungary, Poland, Slovenia

Outcome results

None listed

Effects of single-pill combination of telmisartan/amlodipine and telmisartan/amlodipine/hydrochlorothiazide on 24-hour blood pressure (BP) reduction, 24-h BP variability and office BP control in patients with arterial hypertension – SATELLITE