Severely burned patients
Conditions
Brief summary
• Persistent organ dysfunction (PODS)+death at 28 days, a novel composite endpoint that combines being alive and being free of organ support (inotropes or vasopressors, renal replacement therapy and mechanical ventilation).
Detailed description
• The most important secondary endpoint of this trial will be “time to discharge alive from hospital“., • The other secondary outcomes will be the components of 28-day POD which include mortality, use of inotropes or vasopressors or mechanical circulatory assistance, renal replacement therapy and mechanical ventilation and POD-free days in the first 28 days.
Interventions
Sponsors
Queen's University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Persistent organ dysfunction (PODS)+death at 28 days, a novel composite endpoint that combines being alive and being free of organ support (inotropes or vasopressors, renal replacement therapy and mechanical ventilation). | — |
Secondary
| Measure | Time frame |
|---|---|
| • The most important secondary endpoint of this trial will be “time to discharge alive from hospital“., • The other secondary outcomes will be the components of 28-day POD which include mortality, use of inotropes or vasopressors or mechanical circulatory assistance, renal replacement therapy and mechanical ventilation and POD-free days in the first 28 days. | — |
Countries
Belgium, France, Germany, Italy, Portugal
Outcome results
None listed