Psychosis Associated with Alzheimer’s Disease
Conditions
Brief summary
Change in NPI-C: H+D score
Detailed description
•Change in the CGI-S scale: CGI-S requires the assessor to consider aspects of the psychosis (hallucinations and delusions) prior to providing a global assessment of severity, •Change in the: - NPI-C Core score: hallucinations, delusions, agitation, and aggression domains - NPI-C: Agitation score - NPI-C Core score: Caregiver Distress scale (Hallucinations, Delusions, Agitation, and Aggression domains), •Responder rate defined as NPI-C: H+D score ≥ 40% improvement - Change in CMAI-IPA score - Change in CMAI Total score
Interventions
None listed
Sponsors
Karuna Therapeutics Inc.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in NPI-C: H+D score | — |
Secondary
| Measure | Time frame |
|---|---|
| •Change in the CGI-S scale: CGI-S requires the assessor to consider aspects of the psychosis (hallucinations and delusions) prior to providing a global assessment of severity, •Change in the: - NPI-C Core score: hallucinations, delusions, agitation, and aggression domains - NPI-C: Agitation score - NPI-C Core score: Caregiver Distress scale (Hallucinations, Delusions, Agitation, and Aggression domains), •Responder rate defined as NPI-C: H+D score ≥ 40% improvement - Change in CMAI-IPA score - Change in CMAI Total score | — |
Countries
Belgium, Greece, Hungary, Poland
Outcome results
None listed