ATTR Cardiac Amyloidosis
Conditions
Brief summary
Absolute change in 6 minute walking distance
Detailed description
Proportion of patients experiencing a clinically significant increase in the Kansas City Cardiomyopathy Questionnaire overall summary score (≥5 points), Proportion of patients with meaningful change in NT-proBNP (≥20% decrease);, Any decrease in diuretic dose;, Evaluate the safety profile of dapagliflozin, in terms of adverse events recorded, compared to the SOC.
Interventions
DRUGForxiga 10 mg film-coated tablets
Sponsors
Fondazione Toscana Gabriele Monasterio
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Absolute change in 6 minute walking distance | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients experiencing a clinically significant increase in the Kansas City Cardiomyopathy Questionnaire overall summary score (≥5 points), Proportion of patients with meaningful change in NT-proBNP (≥20% decrease);, Any decrease in diuretic dose;, Evaluate the safety profile of dapagliflozin, in terms of adverse events recorded, compared to the SOC. | — |
Countries
Italy
Outcome results
None listed