A randomized study to investigate central and cerebral hemodynamic effects and volume kinetics of Ringer´s Acetate compared with no intravenous fluids, during experimental hypovolemia compared with euvolemia, in healthy human volunteers.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2023-503946-30-00

Enrollment

Registered

2023-06-26

Start date

2024-03-02

Completion date

2025-10-30

Last updated

2024-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypovolemia

Brief summary

Half-life of cardiac stroke volume relative to baseline

Detailed description

Half-life of intravascular volume relative to baseline, Half-life of MCAv integral relative to baseline

Interventions

DRUGRinger-acetat Fresenius Kabi infusjonsvæske

DRUGoppløsning

Eligibility

Sex/Gender

All

Age

18 Years to 64 Years

Design outcomes

Primary

Measure	Time frame
Half-life of cardiac stroke volume relative to baseline	—

Secondary

Measure	Time frame
Half-life of intravascular volume relative to baseline, Half-life of MCAv integral relative to baseline	—

Countries

Norway

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026