Preventing caRdiovascular collapsE with VasoprEssors duriNg Tracheal IntubatiON: The PREVENTION Randomized Controlled Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

EU CTIS

Registry ID

CTIS2023-503895-25-00

Acronym

IRFMN-9063

Enrollment

320

Registered

2024-03-06

Start date

2024-08-01

Completion date

Unknown

Last updated

2025-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

criticall illness

Brief summary

Mean arterial pressure (MAP) < 60 mmHg, Cardiac arrest

Detailed description

Cardiac arrest within 30 minutes from induction, Mean arterial pressure (MAP) < 60 mmHg, Lowest systolic blood pressure within 30 minutes from induction, Need for a rescue vasopressor, Change in systolic blood pressure from last value before induction to lowest value up to 30 minutes from induction, Severe hypertension (MAP > 120 mmHg) by 30 minutes from induction

Interventions

DRUGNORADRENALINA TARTRATO MONICO 2 mg/ml Concentrato per soluzione per infusione

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure (MAP) < 60 mmHg, Cardiac arrest	—

Secondary

Measure	Time frame
Cardiac arrest within 30 minutes from induction, Mean arterial pressure (MAP) < 60 mmHg, Lowest systolic blood pressure within 30 minutes from induction, Need for a rescue vasopressor, Change in systolic blood pressure from last value before induction to lowest value up to 30 minutes from induction, Severe hypertension (MAP > 120 mmHg) by 30 minutes from induction	—

Countries

Ireland, Italy

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026