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Efficacy and safety of octreotide in laparoscopic hepatectomy surgery: effect on blood loss, need for vasoactive drugs, transfusion requirement.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2023-503613-29-00
Acronym
HEPA-OCT
Enrollment
62
Registered
2023-06-20
Start date
2023-07-18
Completion date
Unknown
Last updated
2023-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic hepatectomy surgery

Brief summary

The main objective of the trial is the reduction of intraoperative bleeding, which will be measured through milliliters of blood lost at the end of surgery, decrease in hemoglobin, hematocrit, platelets and fibrinogen values.

Detailed description

Changes in heart rate and blood pressure during surgery., Need for transfusion of blood products during surgery and later during the immediate perioperative 24-72h., Need for the use of vasoactive drugs during surgery and if needed, we will indicate when they can be withdrawn., Number of clampings and their duration with monitoring of hemodynamic stability during surgery., Hepatic function and its recovery after surgery, control of hemogram and coagulation after 24h, at discharge and at 3 months., Evaluation of admissions after surgery up to three months later related to any post-surgical complication.

Interventions

DRUGOCTREOTIDE

Sponsors

University Clinic Of Navarra
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
The main objective of the trial is the reduction of intraoperative bleeding, which will be measured through milliliters of blood lost at the end of surgery, decrease in hemoglobin, hematocrit, platelets and fibrinogen values.

Secondary

MeasureTime frame
Changes in heart rate and blood pressure during surgery., Need for transfusion of blood products during surgery and later during the immediate perioperative 24-72h., Need for the use of vasoactive drugs during surgery and if needed, we will indicate when they can be withdrawn., Number of clampings and their duration with monitoring of hemodynamic stability during surgery., Hepatic function and its recovery after surgery, control of hemogram and coagulation after 24h, at discharge and at 3 months., Evaluation of admissions after surgery up to three months later related to any post-surgical complication.

Countries

Spain

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026