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A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Belvarafenib as a Single Agent and in Combination with Either Cobimetinib or Cobimetinib Plus Nivolumab in Patients with NRAS-Mutant Advanced Melanoma

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2022-503107-21-00
Acronym
GO42273
Enrollment
15
Registered
2023-11-30
Start date
2021-05-14
Completion date
2025-09-04
Last updated
2025-08-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NRAS-mutant advanced cutaneous melanoma

Interventions

None listed

Sponsors

Genentech Inc.
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Countries

Germany, Norway

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026