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A Phase 1 Study of PRT3789 in Participants with Advanced or Metastatic Solid Tumors with a SMARCA4 Mutation

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2022-502850-14-00
Acronym
PRT3789-01
Enrollment
70
Registered
2023-08-21
Start date
2023-09-25
Completion date
2025-10-01
Last updated
2025-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder cancer, Breast Cancer, Colon adenocarcinoma, Esophageal/gastric cancer, gastroesophageal junction, gastrointestinal cancer, Head and Neck Squamous cell Carcinoma, Lung Adenocarcinoma, Lung Squamous cell carcinoma, non-small cell lung cancer (NSCLC), Ovarian Cancer, Pancreatic Cancer, Skin Cancer/Melanoma, Uterine/Endometrioid Adenocarcinoma

Interventions

None listed

Sponsors

Prelude Therapeutics Inc.
Lead SponsorINDUSTRY

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Countries

France, Germany, Netherlands, Spain

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026